High Sensitivity C-Reactive Protein (hsCRP) Assay

Marking cardiac risk assessment while serving as a biomarker for systematic inflammation

The AHA/CDC Scientific Statement Summary1,2

hsCRP is a global indicator of future vascular events in adults without any previous history of cardiovascular disease (CVD), with acceptable precision levels down to or below 0.3 mg/L

  • hsCRP enhances risk assessment and therapeutic outcomes in primary CVD prevention
  • hsCRP is particularly advantageous for assessing the risk in patients with
                o Framingham 10-year risk scores of 10%-20% and/or
                o LDL levels of <160 mg/dL
  • hsCRP acts as an independent marker for evaluating the possibility of recurrent cardiac events, such as myocardial infarction or restenosis, after percutaneous coronary intervention

1) Pearson TA, et al. Circulation. 2003;107:499-511. http://circ.ahajournals.org/cgi/content/full/107/3/499
2) Ridker PM. Circulation. 2003;107:363-369. http://circ.ahajournals.org/cgi/content/full/107/3/363