Tools

Symbia.net Clinical Workflow Server

Symbia.net and the Symbia™ acquisition workplace share the same intuitive user interface and workflow design of syngo® MI Applications. Current Symbia users can therefore transition seamlessly from workstations to client-server while maintaining the full flexibility and familiar ease of use of syngo MI Applications.

In addition to full SPECT support, including IQ•SPECT reading, Symbia.net also offers PET reading capabilities for oncology, cardiology and neurology. This makes Symbia.net an integrated molecular imaging platform.

Cardiology Engine SPECT Corridor4DM
Cardiology Engine SPECT Corridor4DM, Advanced
Cardiology Engine SPECT Corridor4DM, Premium

Cardiology Engine SPECT Corridor4DM assists in the diagnosis and quantitative assessment of coronary artery disease by enabling the visualization of SPECT studies as well as quantified perfusion assessment. 

Cardiology Engine SPECT Corridor4DM

The Corridor4DM application includes comprehensive interactive processing and display, generation of 2D, 3D and polar maps images, calculation of ventricular volumes, myocardial mass and ejection fraction for gated SPECT studies and utilizes gated bloodpool data to calculate left ventricular Ejection Fraction. Compare perfusion and functional polar maps to gender-matched normal files, which includes additional support for attenuation correction. Also included are a normal database generator and the ability to create reports within the Corridor4DM application. 

Cardiology Engine SPECT Corridor4DM, Advanced
The Corridor4DM, Advanced application includes above functionality and adds the following:
cardio•Flash, a three dimensional iterative reconstruction method with resolution recovery and scatter correction, can be used to shorten myocardial perfusion imaging by as much as 50%. The reconstructed data has similar, or even better, image quality when compared to a full-time MPI scan with a conventional reconstruction using filtered back projection. To aid in patient throughput, this engine includes complete syngo® MI Workflows, specifically designed to acquire MPI SPECT scans with half-time acquisition parameters and optimized reconstruction settings and filters. 

Cardiology Engine SPECT Corridor4DM, Premium
The Corridor4DM, Premium application includes above functionality and adds the following:
Corridor4DM Coronary Overlay, superimposes the coronary tree onto the 3D renderings of the myocardial surface to aid in the visualization of perfusion defects. 

The Corridor4DM application is an OEM product developed and supported by INVIA.

Cardiology Engine SPECT Cedars
Cardiology Engine SPECT Cedars, Advanced
Cardiology Engine SPECT Cedars, Premium
SPECT Cardiology Engines assist in the diagnosis and quantification of coronary artery disease as well as in risk stratification for acute cardiac events.
Cardiology Engine SPECT Cedars
The Cedars engine calculates a comprehensive set of cardiac parameters including ejection fractions, volumes, wall motion including right ventricular free wall motion in Quantitative Blood Pool SPECT (QBS), wall thickening, perfusion (%).Quantitative Perfusion SPECT (QPS) allows for the quantitation of prone SPECT data and of serial perfusion changes. Both 20 and AHA-17 segment scoring models are available. In addition to calculating an Eccentricity Index, Quantitative Gated SPECT (QGS) also calculates a more regional measure of the left ventricle shape known as the Shape Index. Displays include gated slices with contours, a motion frozen display which results in better resolution and contrast by eliminating motion of the cardiac cycle, interactive 3D images and polar maps. Manual override of contours and DICOM compatible output are additional features. Outputs include DICOM secondary capture files, result files, as well as the ability to generate an AVI file format.
Cardiology Engine SPECT Cedars, Advanced
The Cedars, Advanced engine includes above functionality and adds the following:
cardio•Flash, a three dimensional iterative reconstruction method with resolution recovery and scatter correction, can be used to shorten myocardial perfusion imaging by as much as 50%. The reconstructed data has similar, or even better, image quality when compared to a full-time MPI scan with a conventional reconstruction using filtered back projection. To aid in patient throughput, this engine includes complete syngo® MI Workflows, specifically designed to acquire MPI SPECT scans with half-time acquisition parameters and optimized reconstruction settings and filters.
Cardiology Engine SPECT Cedars, Premium
The Cedars, Premium engine includes above functionality and adds the following:
Cedars Fusion/Coronary Overlay provides information in the form of multi-modality fusion and extracted coronary artery trees from the syngo Circulation Application in to the Cedars Quantitative Gated SPECT (QGS) and Quantitative Perfusion SPECT (QPS) applications for the purposes of visually enhancing the interpretation of the MPI exam. The Cedars application superimposes the coronary tree onto the 3D renderings of the myocardial surface to Siemens SPECT to aid in the visualization of perfusion defects.
The Cedars application is an OEM product developed and supported by Cedars Sinai.

Emory Cardiac Toolbox Suite
The Emory Cardiac Toolbox is a comprehensive collection of processing tools that highly automate clinical cardiology procedures.
Emory Cardiac Toolbox Suite
The Toolbox features a complete CEqual package with databases. In addition, cardiac parameters, such as Ejection Fraction, Volumes, Myocardial Mass, Wall Thickening and Transient Ischemic Dilatation, are calculated. The program also utilizes a 3D image fusion technique that superimposes generic coronary arterial trees onto 3D rendered surfaces. An interactive display permits arbitrary 3D rotation of the beating heart for the simultaneous evaluation of wall motion and perfusion. Standard functionality also includes a Gated Quality Control Analysis tool to assess gating activity. In addition, outputs include DICOM secondary capture and result files to aid in the quick review of previously processed data.

Oncology Engine SPECT
Oncology Engine SPECT, Advanced
Oncology Engine SPECT, Premium
SPECT Oncology Engines provide productivity features to allow half-time acquisition, as well as advanced 3D visualization tools.
Oncology Engine SPECT
This engine includes a 3D iterative reconstruction method with resolution recovery and scatter correction. It also includes statistics-based adaptive de-noising and de-blurring of planar images and longitudinal whole body bone scans. It can be used to shorten the acquisition time of planar images, bone scans or SPECT studies without loss in image quality. This reconstruction method can also improve overall image quality with better contrast, higher resolution and decreased image noise when used to reconstruct full-time studies.
The Oncology Engine SPECT includes syngo® MI Workflows with half-time acquisition parameters and optimized reconstruction settings and filters, specifically designed to acquire whole-body SPECT scans in the time of a conventional whole body bone scans and to increase the scan speed of whole-body bone scans to shorten scan time.
Oncology Engine SPECT, Advanced
The Advanced engine includes above functionality and adds the following:
A volumetric visualization technique that provides fused anatomical and functional volumes into orthogonal planes using multiple layout views or full-screen mode.
This engine provides tools to evaluate and display SPECT (and independently acquired CT) images and results, enabling customized user defined formats, image reorientation in any axis, an array of color look-up tables and filming options. Standard features include: viewing of SPECT and CT DICOM images including image fusion display for registered series; common display tools such as correlated cursors, quantitative color bar and interactive pixel value; default CT image windows; display of CT maximum intensity projections (MIP); 3D Reorientation of volume data; region of interest (ROI) and volume of interest analysis and visualization.
Oncology Engine SPECT, Premium
The Premium includes above functionality and adds the following:
Volume rendering techniques for both SPECT and separately acquired CT image data. It offers independent control of color, opacity and shading of up to four tissue classes, as well as predefined VRT (Volume Rendering Technique) settings which can be selected via an image gallery. It also offers the ability to interactively manipulate the levels of fusion ranging from CT only to SPECT only and various scaled combinations. As MPR, MIP, SSD or VRT are different visualization modes possible with the same dataset, the user can arbitrarily switch between these modes as well as switch the actual display segment to full-screen mode. All modes can be registered and linked so the image manipulations including interactive slice browsing and image rotation are viewed in synchronization.
The integrated editing package allows segmentation of 3D datasets either with manual contour creation, thresholding, or volume growing operations. Dataset confinement is possible either using a ClipBox or a variable editing slab. Image quality can be improved with morphological operators such as Erosion and Dilatation.

SPECT Neurology Add-on
The Neurology Add-on adds the ability to quantify SPECT neurology examinations.
SPECT Neurology Add-on
With the use of optimized workflows included in this SPECT Neurology Add-on, you can combine standardized anatomy and a comprehensive normal database with advanced fusion techniques, to enable automatic correlation of the patient’s study with an average brain for quick computation of abnormalities. The fusion engine produces results that are reliable and reproducible between multiple sessions and multiple users. The quantification tools include voxel-by-voxel and regional evaluation of abnormal brain perfusion and automatic positioning of anatomical regions of interest which are optimized for evaluation of dementia. Additional anatomical brain regions of interest are possible, which makes this application flexible to evaluate a number of neurological disorders. In addition, several anatomical regions may be selected for quick assessment of a single patient scan or for quantitative comparison to other scans. Unique fusion techniques, automated evaluation steps and comprehensive quantification tools meet the needs of the emerging SPECT, or SPECT and independently acquired CT neurological evaluations. A reporting mechanism is also incorporated to help ensure consistent patient reporting.
The SPECT Neurology Add-on also allows further qualitative and quantitative comparison of brain images by co-registration of functional data with a reference template (The Talairach atlas). Quantitative analysis of brain images in both Talairach and patient space and according to arterial basins, Brodmann’s functional areas, or user-defined areas which can be saved and reapplied to subsequent patient data. The engine also includes sequential comparison of brain function (up to 2 datasets) and comparison of functional data with a normal database.

Cardiology Engine SPECT/CT Corridor4DM
Cardiology Engine SPECT/CT Corridor4DM, Advanced
Cardiology Engine SPECT/CT Corridor4DM assists in the diagnosis and quantitative assessment of coronary artery disease by enabling the visualization of SPECT studies as well as quantified perfusion assessment.
Cardiology Engine SPECT/CT Corridor4DM
The Corridor4DM application includes comprehensive interactive processing and display, generation of 2D, 3D and polar maps images, calculation of ventricular volumes, myocardial mass and ejection fraction for gated SPECT studies and utilizes gated bloodpool data to calculate left ventricular ejection fraction. Compare perfusion and functional polar maps to gendermatched normal files, which includes additional support for attenuation correction. Also included are a normal database generator and the ability to create reports within the Corridor4DM application.
Cardiology Engine SPECT/CT Corridor4DM, Advanced
The Corridor4DM, Advanced application includes above functionality and adds the following:
Calcium Scoring (Agatston, volume and calcium mass) to assess the risk of a cardiac infarct within user defined regions for up to four coronary arteries. Visualization and
localization consists of a functional VRT (Volume Rendering Technique) fused with an anatomical VRT, with a unique, real-time reorientation based on 3D volumetric images. The resulting areas of calcification or coronary arteries are overlaid on the VRT. One-Click Heart Isolation allows the user to isolate the heart from the surrounding tissue, while correlation of calcium scoring results with MPI slices and Fused VRT allows for easy navigation through areas of calcification.
The Corridor4DM application is an OEM product developed and supported by INVIA.

Cardiology Engine SPECT/CT Cedars
Cardiology Engine SPECT/CT Cedars, Advanced
The SPECT/CT Cardiology Engines assist in the diagnosis and quantification of coronary artery disease as well as in risk stratification for acute cardiac events.
Cardiology Engine SPECT/CT Cedars

The Cedars engine calculates a comprehensive set of cardiac parameters including ejection fractions, volumes, wall motion including right ventricular free wall motion in Quantitative Blood Pool SPECT (QBS), wall thickening, perfusion (%). Quantitative Perfusion SPECT (QPS) allows for the quantitation of prone SPECT data and of serial perfusion changes. Both 20 and AHA-17 segment scoring models are available. In addition to calculating an Eccentricity Index, QGS also calculates a more regional measure of the left ventricle shape known as the Shape Index. Displays include gated slices with contours, a motion frozen display which results in better resolution and contrast by eliminating motion of the cardiac cycle, interactive 3D images and polar maps. Manual over-ride of contours and DICOM compatible output are additional features. Outputs include DICOM secondary capture files, result files as well as the ability to generate an AVI file format.
Cardiology Engine SPECT Cedars, Advanced
The Cedars, Advanced engine includes above functionality and adds the following:
Calcium Scoring (Agatston, volume and calcium mass) to assess the risk of a cardiac infarct within user-defined regions for up to four coronary arteries. Visualization and localization consists of a functional VRT (Volume Rendering Technique) fused with an anatomical VRT, with a unique, real-time reorientation based on 3D volumetric images. The resulting areas of calcification or coronary arteries are overlaid on the VRT. One-Click Heart Isolation allows the user to isolate the heart from the surrounding tissue, while correlation of calcium scoring results with MPI slices and Fused VRT allows for easy navigation through areas of calcification.
The Cedars application is an OEM product developed and supported by Cedars Sinai.

Oncology Engine SPECT/CT
Oncology Engine SPECT/CT, Advanced
The Oncology Engine SPECT/CT facilitates lesion detection by enabling the visualization, volumetric analysis and fusion of single SPECT/CT studies.
Oncology Engine SPECT/CT
A volumetric visualization technique that provides fused anatomical and functional volumes into orthogonal planes using multiple layout views. This engine provides tools to evaluate and display SPECT/CT images and results, enabling customized user defined formats, image reorientation in any axis, an array of color look-up tables and filming options. Standard features include: viewing of SPECT and CT DICOM images including image fusion display for registered series; common display tools such as correlated cursors, quantitative color bar and interactive pixel value; default CT image windows; display of CT maximum intensity projections (MIP); 3D Reorientation of volume data; region of interest (ROI) and volume of interest analysis and visualization.
Oncology Engine SPECT/CT, Advanced
includes above functionality and adds the following:
Advanced 3D image display capabilities and automated or manual registration/fusion of images from independently acquired modalities (e.g., CT, MR). These features include interactive 3D volume rotation, multi-planar reconstruction (MPR) user defined slice thickness, and an array of co-registration techniques, such as visual, landmark and automated registration.

SPECT/CT Neurology Engine
SPECT/CT Neurology Engine, Advanced
SPECT/CT Neurology Engines add the ability to quantify SPECT neurology examinations.
SPECT/CT Neurology Engine
Provides tools to evaluate and display SPECT/CT neurology images and results, enabling customized user defined formats, image reorientation in any axis, an array of color look-up tables and filming options. Standard features include: viewing of SPECT and CT DICOM images including image fusion display for registered series; common display tools such as correlated cursors, quantitative color bar and interactive pixel value; default CT image windows; display of CT maximum intensity projections (MIP); 3D reorientation of volume data; region of interest (ROI) and volume of interest analysis and visualization.
SPECT/CT Neurology Engine, Advanced
With the use of optimized workflows included in this SPECT/CT Neurology Engine, Advanced, one can combine standardized anatomy and a comprehensive normal database with advanced fusion techniques, to enable automatic correlation of the patient’s study with an average brain for quick computation of abnormalities. The fusion engine produces results that are reliable and reproducible between multiple sessions and multiple users. The superior quantification tools include voxel-by-voxel and regional evaluation of abnormal brain perfusion and automatic positioning of anatomical regions of interest which are optimized for evaluation of dementia. Additional anatomical brain regions of interest are possible which makes this application flexible to evaluate a number of neurological disorders. In addition, several anatomical regions may be selected for quick assessment of a single patient scan or for quantitative comparison to other scans. Unique fusion techniques, automated evaluation steps, and comprehensive quantification tools meet the needs of the emerging SPECT or SPECT and independently acquired CT neurological evaluations. A reporting mechanism is also incorporated to help ensure consistent patient reporting.
The SPECT/CT Neurology Engine, Advanced, also allows further qualitative and quantitative comparison of brain images by co-registration of functional data with a reference template (The Talairach atlas). Quantitative analysis of brain images in both Talairach and patient space and according to arterial basins, Brodmann’s functional areas, or user defined areas which can be saved and reapplied to subsequent patient data. The engine also includes sequential comparison of brain function (up to two datasets) and comparison of functional data with a normal database.

SPECT Cardiac Processing
SPECT Processing
SPECT/CT Processing

Symbia.net can be configured to allow full image reconstruction and processing on all clients.
SPECT Cardiac Processing

Cardiac and General processing features, including:

  • Processing of up to four series simultaneously with up to six energy windows per series
  • Simultaneous reconstruction of gated and non-gated series
  • Separate reconstruction parameters per series
  • Filtered back-projection and OSEM 2D Reconstructions
  • Interactive 3D Masking/Centering
  • 3D Elliptical Masking (general)
  • Chang's Attenuation Correction (general)

Quality Control features, including:

  • Sinogram, linogram, and summed image
  • Cine with reference line
  • Automatic and manual motion correction
  • Gated histogram review

3D reorientation features, including:

  • Interactive free angle reorientation of reconstructed series
  • Processing up to four series simultaneously

Cardiac Planar Gated Blood Pool features, including:

  • Left and right ventricular EF analysis
  • Regional EF analysis
  • Automated image filtering
  • Automatic or manual ROI determination
  • Functional image creation
  • Curve Analysis
  • Filling and emptying rate analysis

Shunt Analysis features, including:

  • Automatic composite creation
  • Curve smoothing and fitting options
  • Integral calculation for patient and shunt curve
  • Shunt Qp/Qs via Area Method
  • Shunt Qp/Qs via Height Method

SPECT Processing

Image Fusion features, including:

  • Automatic matrix interpolation and registration for SPECT to CT or MR fusion
  • Adjustable alpha blending display
  • Landmark registration technique

Lung Analysis features, including:

  • Total or segmented (2 or 3) analysis
  • Ventilation and perfusion quantitation
  • Left and right lung and segment ratio comparison
  • Geometric mean calculation

Thyroid Analysis features including:

  • Automatic or manual ROI determination
  • Syringe or dose calibrator residual activity methods
  • Uptake, count rate, area and volume calculations
  • Single lobe processing
  • 6 and 24 hour Uptake

Renal Analysis features, including:

  • Automatic or manual ROI determination
  • Gates GFR
  • Oberhausen ERPF
  • Itoh ERPF
  • Oriuchi MAG3
  • MAG3 without blood sample
  • Transplant
  • Captopril comparison
  • Bubeck (TER) processing
  • Curve analysis
  • Right and left ratio
  • Body surface calculation for adult or pediatric
  • Flow and excretion calculations

Gastric Emptying Analysis features, including:

  • Automatic or manual ROI determination
  • Dual isotope/energy window support
  • Geometric mean calculation
  • Curve fitting routines
  • Liquid / solid processing
  • Emptying calculations

Hepatobiliary features, including:

  • Automatic or manual ROI determination
  • Ejection fraction calculations
  • Dynamic and Static Methods supported
  • User-defined interval ejection fraction processing

Brain Analysis features, including:

  • ROI quantitation and ratio analysis
  • Bloodflow analysis
  • Patlok plot and cerebral bloodflow
  • Lassen Method
  • IMP
  • IMP-ARG
  • NIMS

SPECT/CT Processing
SPECT/CT processing includes the above functionality and adds the following:

  • Advanced 3D image display capabilities and automated or manual registration/fusion of images from independently acquired modalities (e.g., CT, MR)
  • Flash 3D: an innovative SPECT OSEM 3D algorithm providing higher contrast, higher resolution and decreased image noise compared to OSEM 2D and FBP.
  • CT attenuation correction
  • Scatter correction

PET Oncology
PET Cardiology
PET Neurology

Symbia.net can be configured with PET/CT reading capabilities for oncology, cardiology and neurology.
PET Oncology
Features include:

  • Viewing of PET and CT DICOM images including image fusion display for registered series
  • Common display tools such as correlated cursors, quantitative color bar and interactive pixel value
  • Preset of PET SUV color tables
  • Preset of CT image windows
  • Display of CT and PET maximum intensity projections (MIP)
  • 3D reorientation of volume data
  • Region of interest (ROI) and volume of interest (VOI) analysis and visualization including standard uptake value (SUV) calculation
  • ROI and curve creation for dynamic PET series

PET Cardiology
Corridor4DM PET Suite includes:

  • A comprehensive advanced quantification and visualization software package for nuclear cardiology professionals developed by INVIA and the University of Michigan. Corridor4DM integrates LV function, perfusion and FDG metabolism in a single solution for the quantification, display, and reporting of cardiac PET studies.
  • Cedars PET Suite includes:
  • A comprehensive set of quantitation program for the evaluation of PET myocardial studies.

PET Neurology
Features include:

  • Advanced neurological evaluation by providing a clinically focused software solution for brain analysis when used with PET and PET/CT imaging

IDL Runtime
IDL Developer Suite

Symbia.net allows users to program facility-specific applications through the use of IDL.
IDL Runtime

The IDL Runtime software allows the seamless integration and execution of custom applications within a workflow on Symbia.net.

IDL Developer Suite
The IDL Developer Suite provides the capability to develop custom applications
using the IDL Developer software and integrate them in workflows on Symbia.net using the IDL Runtime software.

IDL is developed and supported by ITT Visual Information Solutions, formally Research Systems Inc. (RSI)

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